Organisation of the EUCAST subcommittee on Anti-Mycobacterial Susceptibility Testing (AMST)
Remit of the EUCAST AMST subcommittee
- Define and standardise a reference methodology for MIC-determination of the M. tuberculosis complex and non-tuberculous mycobacteria (NTM).
- Develop a SOP for the EUCAST reference MIC method.
- Develop a SOP for the calibration of surrogate methods against the EUCAST reference MIC method.
- Develop a technical reference protocol for MIC-determination of antimycobacterial agents dissolved in DMSO (Dimethyl Sulfoxide).
- Define a set of quality control strains.
- Organise studies to establish reproducibility of the reference method in at least three laboratories.
- Organise studies to generate MIC distributions for the reference strains. The reference MICs will be performed in at least three reference laboratories.
- Interact with the EUCAST Steering Committee in the setting of breakpoints for antimycobacterial agents.
- Define the relevance of molecular testing and mutation frequencies and their relationship to phenotypic testing.
EUCAST-AMST Subcommittee (SC) members 2024
- Emmanuelle Cambau (France), Chair.
GHU APHP-Nord, Université de Paris, Inserm UMR 1137 IAME, Service de Mycobactériologie spécialisée et de référence, Hôpital Bichat - batiment principal locaux IMEA rez de chaussée, 46 rue Henri Huchard 75018 Paris, France (email: emmanuelle.cambau[at]aphp.fr) - Jim Werngren (Sweden), SC Secretary
- Daniela Cirillo (Italy), AMST SC member
- Miguel Santin (Spain), AMST SC member
- Fernando Alcaide (Spain), AMST SC member
- Emmanuel André (Belgium), AMST SC member
- Jakko van Ingen (The Netherlands), AMST SC member
- Miguel Viveiros (Portugal), General committee/AMST representative
- Christoffer Lindemann, EUCAST Steering committee observer
- Gunnar Kahlmeter (Sweden), EUCAST Steering committee observer, curator of the EUCAST MIC distribution database, webmaster
- Christian Giske (Sweden), EUCAST Steering committee observer
The AMST General Committee:
|
Member |
Initials |
Committee |
Country |
|
Adrian Zelazny |
AZ |
AMST General committee |
US |
|
Alexandra Aubry |
AA |
AMST General committee |
France |
|
Anne Torunn |
AT |
AMST General committee |
Norway |
|
Bettina Schulthess |
BS |
AMST General committee |
Switzerland |
|
Breida Boyle |
BB |
AMST General committee |
Ireland |
|
Christian Giske |
CG |
EUCAST Steering committee |
Sweden |
|
Christoffer Lindemann |
CL |
EUCAST Steering committee |
Norway |
|
Daniela Cirillo |
DC |
AMST steering committee |
Italy |
|
Danijela Rajkovic |
DR |
AMST General committee |
Montenegro |
|
Despo Pieridou |
DP |
AMST General committee |
Cyprus |
|
Diana Machado |
DM |
AMST General committee |
Portugal |
|
Dissou Affolabi |
DA |
AMST General committee |
Benin |
|
Dorte Bek Folkvardsen |
DF |
AMST General committee |
Denmark |
|
Dragana Vuković |
DV |
AMST General committee |
Serbia |
|
Emanuele Borroni |
EB |
AMST General committee |
Italy |
|
Emmanuel André |
EA |
AMST steering committee |
Belgium |
|
Emmanuelle Cambau |
EC |
Chair AMST |
France |
|
Erik Svensson |
ES |
AMST General committee |
Denmark |
|
Fernando Alcaide |
FA |
AMST steering committee |
Spain |
|
Gunnar Kahlmeter |
GK |
Tech. cord. Steering committee |
Sweden |
|
Hanne-Leena Hyyrylainen |
HH |
AMST General committee |
Finland |
|
Inna Friesen |
IF |
AMST General committee |
Germany |
|
Jakko van Ingen |
JVI |
AMST steering committee |
The Netherlands |
|
Jim Werngren |
JW |
Secretary AMST |
Sweden |
|
Kadri Klaos |
KK |
AMST General committee |
Estonia |
|
Marianne Antar |
MA |
AMST General committee |
Lebanon |
|
Martin Kuhns |
MK |
AMST General committee |
Germany |
|
Miguel Viveiros |
MV |
AMST steering committee |
Portugal |
|
Miguel Santin |
MS |
AMST steering committee |
Spain |
|
Nazir Ismail |
NI |
AMST General committee |
South Africa |
|
Olha Konstantynovska |
OK |
AMST General committee |
Ukraine |
|
Peter Sander |
PS |
AMST General committee |
Switzerland |
|
Rrezarta Bajrami Halili |
RB |
AMST General committee |
Kosovo |
|
Špela Klemen |
SK |
AMST General committee |
Slovenia |
|
Sönke Andres |
SA |
AMST General committee |
Germany |
|
Thomas Schön |
TS |
AMST General committee |
Sweden |
The AMST Network Laboratories are listed here.
Information for industry aiming to bring agents to EUCAST for review and revision of breakpoints or a new agent to EMA for registration is available at Information for industry.
