| Endocarditis AST guidelines |
Guidance for the use of the new endocarditis breakpoints (released as part of the v 15.0 (2025) breakpoint table) is released. |
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2025/12/05 |
| Breakpoint table 15.0 on consultation |
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2024/12/05 |
| Antifungal breakpoints and updated 2 Dec 2024 |
The breakpoint tables for antifungal agents have been revised. |
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2024/12/02 |
| Antifungal overview of breakpoints and ECOFFs revised |
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2024/12/02 |
| Anidulafungin and Micafungin rationale documents updated 2024 |
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2024/11/25 |
| Endocarditis breakpoints |
Following the now finalised consultation, the comments from colleagues and responses from EUCAST are now published. |
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2024/11/20 |
| Updated guidance on S. maltophilia |
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2024/11/15 |
| Response to public consultation |
EUCAST comments and responses to the public consultation on changing breakpoints for S. pneumoniae and Streptococcus viridans published. |
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2024/10/24 |
| RAST tables - Error related to Acinetobacter corrected |
An error related to recommendations for Acinetobacter baumannii and ciprofloxacin corrected. |
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2024/09/23 |
| Aminoglycoside rationale documents updated |
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2024/09/19 |
| General consultation on proposed breakpoints for endocarditis |
The public consultation is open between 14 Sept and 25 Oct, 2024. |
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2024/09/14 |
| Cefiderocol has been addded to "When there are no breakpoints" |
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2024/09/03 |
| New Rationale Document |
RDs for aztreonam-avibactam and cefepime-enmetazobactam available |
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2024/07/04 |
| RAST from EUCAST with breakpoints for Salmonella enterica |
EUCAST has developed the Enterobacterales RAST further to include 4, 6, 8 and 16-20 h breakpoints also for Salmonella enterica. Some QC criteria were also updated. |
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2024/07/04 |
| Expert rules updated |
Expert rules updated for Enterobacterales and Enterococcus. |
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2024/06/30 |
| Updated guidance document |
"Intravenous use of fosfomycin" updated 28 May, 2024.
See guidance documents. |
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2024/05/28 |
| Aztreonam-avibactam and cefepime-enmetazobactam breakpoints available |
Breakpoints published as addenda to the regular breakpoint table 14.0, 2024. |
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2024/05/22 |
| The Belgian NAC presented |
The Belgian NAC (National AST Committee) is presented. |
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2024/05/18 |
| New consultations |
New consultation published. |
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2024/05/07 |
| EUCAST advice on the development of reference methods for MIC testing of new agents |
The development of new agents require agreement and acceptance of the data generated in support of decisions on clinical breakpoints, wild type MIC distributions, ECOFFs and routine susceptibility testing correlates. EUCAST and CLSI both favour the unadulterated use of ISO recommended reference broth microdilution for this purpose, and only occasionally is there good reason to deviate from this. When this is considered necessary it is strongly adviced that this is with the agreement and full understanding of standards committees and agencies, such as CLSI, EUCAST, FDA and EMA. |
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2024/04/24 |
| When there are no breakpoints - revised 29 February 2024 |
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2024/02/29 |
| Advising pharmaceutical industry |
The advice to pharmaceutical industry has been further developed. Go to the "Information for industry" page. |
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2024/02/14 |
| Rezafungin Rationale Document published |
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2024/02/11 |
| Updated guidance on ATU |
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2024/02/08 |
| Revised "EUCAST response to the fosfomycin consultation" |
Because of a printing error in this document a new version was uploaded. |
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2024/02/06 |
| ECCMID 2023 EUCAST posters available |
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2024/01/10 |
| Maps updated for 2024 EUCAST uptake |
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2024/01/10 |
| Graphs to illustrate ATUs updated 2024 |
EUCAST provides a yearly update of the ATUs in relation to zone diameter and MIC distributions. The 2024 update now available. |
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2024/01/09 |
| Files demonstrating the correlation between MIC and zone diameters now updated |
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2024/01/09 |
| Several Rationale Documents updated |
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2024/01/05 |
| The 2024 EUCAST breakpoint table available for consultation |
The period for consultation is 5 - 19 December, 2024. Comments and questions should be addressed to erika.matuschek[at]eucast.org or gunnar.kahlmeter[at]eucast.org. |
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2023/12/05 |
| Fosfomycin - response to consultation and guidance on IV use |
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2023/12/05 |
| New fosfomycin IV rationale document published |
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2023/11/23 |
| Comments and responses to consultations |
Comments and EUCAST responses to the open consultations on Brucella melitensis and Bacillus anthracis proposed breakpoints and methods are now published. |
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2023/11/21 |
| VetCast rationale documents for general consultation. |
Rationale documents on the use of amoxicillin-clavulanic acid and benzylpenicillin in dogs and horses available for consultation (comments no later than 8 January, 2024) |
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2023/11/15 |
| RAST breakpoints for proplonged incubation published in JAC |
The breakpoints for follow-up incubation, beyond 8h, were recently published on the EUCAST website. An update is now also available in the Journal of Antimicrobial Chemotherapy |
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2023/10/30 |
| Updated document from AFST |
Updated document from AFST "Method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for yeasts" (Edef 7.4, 13 October, 2023). |
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2023/10/13 |
| Updated website statistics |
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2023/10/05 |
| SOP 12 and 13 published |
Two SOPs related to the determination of appropriate disk content (potency) and Muller-Hinton agar quality published |
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2023/09/21 |
| Updated guidance from the EUCAST AFST subcommittee |
Updated breakpoints and ECOFFs and QC-tables
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2023/08/14 |
| Thermo Fisher Scientific Sensititre broth external contamination. |
Visit the Warnings page to read the full warning. |
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2023/08/01 |
| Public consultation on IV Fosfomycin published |
The consultation period is 12 July - 12 September, 2023. |
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2023/07/12 |
| A revised version of the guidance on "What to do when there are no breakpoints" published |
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2023/06/30 |
| New version of breakpoint tables because of added agents to the table for anaerobic bacteria |
The breakpoint tables have been updated from 13.0 (1 Jan, 2023) to 13.1 (29 June, 2023). This allows the AST of several additional agents for anaerobic bacteria. There is a matching update of QC tables. |
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2023/06/29 |
| Updated QC tables |
QC tables were updated to match several breakpoints for agents added for anaerobic bacteria. |
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2023/06/29 |
| The EUCAST FAQ updated |
EUCAST updates a document listing frequently asked questions. The file was updated 2023-06-14 |
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2023/06/14 |
| Updates to RAST breakpoints |
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2023/06/07 |
| Additional agents in EUCAST RAST |
Breakpoints for several agents have been added to the RAST tables. Breakpoint and QC tables, methodology documents and calibration files have all been updated. |
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2023/04/25 |
| Zone diameter distributions re-calibrated |
A new algorithm and software has been created through which wild type inhibition zone diameter distributions can be calculated and ECOFFs allocated. |
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2023/04/25 |
| General committee meetings 2022 and 2023 |
The EUCAST annual General Committee meeting is open to anyone attending ECCMID. Minutes will eventually be posted. Minutes from the 2022 committee meeting in Lisbon 2022 are available.
EUCAST Annual General Committee Meeting, during ECCMID 2023
Monday 17 April, 9.30 – 10.30 am, Meeting Room: Room 173, Bella Sky Hotel. |
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2023/04/08 |
