Breakpoints are part of a system for categorising microorganisms as susceptible (S and I) and resistant (R) to agents approved for use in the treatment of infectious diseases. Below are links to the yearly updated breakpoint tables, but other parts of the system are equally important. These are for example "Expert Rules" and "Expected Phenotypes", "What to do when there are no breakpoints" (and other guidance documents), how to cope with "IE", "Dash", "Breakpoints in brackets" and disease specific breakpoints. All major changes have been subjected to public consultation and following these will facilitate understanding the EUCAST process.

• Clinical breakpoints (v 14.0) - file for printing (1 Jan, 2024 - 31 Dec 2024)
• Clinical breakpoints (v 14.0)  - file for screen (1 Jan, 2024 - 31 Dec 2024)
• Aztreonam-avibactam - Addendum (22 May, 2024). Rationale Document available. QC criteria available.
• Cefepime-enmetazobactam - Addendum (22 May, 2024). Rationale document available. QC criteria available.
• Clinical breakpoints - fungi
• Dosages (v 14.0) - file for printing and screen (1 Jan, 2024).

Breakpoint table v 15.0 consultation 5 Dec - 16 Dec, 2024. The major changes between the 2024 and 2025 breakpoint tables are listed as part of the consultation. To take full advantage of the new table and the new endocarditis breakpoints, see the guidance on reporting susceptibility testing in endocarditis pathogens.

Make sure the device you are using for the presentation of tables can correctly display footnotes (Note₁,Note²) and other typographical tools. 

• EUCAST instruction video on how to use the breakpoint table - download here. The instruction video needs updating since the advice on what to do when there are no breakpoints has been further developed and the suggestion given in the video is no longer valid. See Guidance document: When there are no breakpoints"

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Breakpoints published in Addendum during the year will be part of the next Clinical breakpoint table. Older, no longer valid, breakpoint tables can be accessed through the archive. 

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Definitions of clinical breakpoints and epidemiological cut off values

Modified definitions valid from 1 January, 2019.