24.02.2022
ECOFFs – the why, the how and the don´ts of EUCAST epidemiological cutoff values.
Identifying the MIC wild type distribution and its delineation of species targeted for receiving antimicrobial agent breakpoints is an important first step for determining clinical breakpoints. Having the main responsibility in EUCAST for characterizing the wild-type distributions and the setting of epidemiological cutoff values (ECOFFs), we explain the why, the how and frequent misconceptions of wild-type MIC distributions and ECOFFs.
A narrative review in CMI on the use of ECOFFs is now available in CMI.
