04.10.2021

General consultation on breakpoints for anaerobic bacteria

EUCAST general and public consultation on breakpoints for anaerobic bacteria. Theconsultation pertains to the clinical breakpoints for Bacteroides spp., Prevotella spp., Fusobacterium necrophorum, Clostridium perfringens and Cutibacterium acnes that have now been reviewed against the MIC and zone diameter distributions that were produced as part of the development. Several breakpoints were revised and are now different from those originally set 15 years ago. In general, revised breakpoints are more species-specific than previously. The intention of EUCAST is to introduce the clinical breakpoints as the backbone of the recently developed and validated 16 - 20 hour disk diffusion methodology on FAA medium. This was described separately.